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Restylane® Defyne

in Reno, Nevada

At JanigaMDs, we offer advanced dermal filler treatments designed to restore youthful volume and smooth facial lines. Restylane® Defyne is a hyaluronic acid filler specifically formulated to treat deeper wrinkles and folds while maintaining natural facial movement. Using innovative XpresHAn technology, Restylane® Defyne provides flexible support for natural-looking, refreshed results.

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What is Restylane® Defyne?

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Restylane® Defyne is a hyaluronic acid dermal filler created to replenish volume loss and reduce moderate lines. Hyaluronic acid is a naturally occurring substance in the body that hydrates the skin and gives it elasticity for a smooth, firm texture. It also helps stimulate collagen production, a protein that further aids in elasticity and skin volume. By creating a subtle plumping effect, fillers can smooth wrinkles, fill in facial folds, and add definition.

Created with Galderma’s XpresHAn technology, the hyaluronic acid particles in the Restylane Defyne formula are cross-linked, providing flexibility and smoothness. This flexibility restores youthful volume with dramatic rejuvenation while maintaining natural facial movement to avoid an “overdone” look.

Reasons for Restylane Defyne Treatment

This filler is specifically designed to fill in deep smile lines (nasolabial folds) that run from the corners of the nose to the mouth, smooth marionette lines, which run from the corners of the mouth to the chin, address moderate-to-severe mid-face volume loss, enhance your facial expressions, and provide rejuvenation in the lower face. The structured formula is also an effective choice for minimally invasive, non-surgical chin augmentation.

Defyne can be used alone or in combination with other Restylane fillers, like Restylane Lyft, Restylane Refyne, and Restylane Silk, to treat other areas of the face, like the lips, cheeks, and under-eye hollows.

Before Your Restylane Defyne Procedure

Individuals 21 years and older with mild to moderate wrinkles and folds around the nose and mouth can often benefit from Restylane Defyne. Good candidates will be in good health overall and have realistic expectations for their procedure. People with active areas of infection should not receive injections in those areas. A consultation with Dr. Jennifer Janiga or her associates can help to determine if Restylane treatments are right for you. Alcohol and blood-thinning medications or herbal supplements should be avoided for a few days before treatment.

Your Restylane Defyne Procedure

Restylane Defyne injections are performed by Dr. Janiga or one of our experienced injectors. Before your injection, a topical anesthetic is usually applied.  and Restylane® Defyne contains lidocaine, which is a local anesthetic to give added comfort. Then, with a fine-gauge needle, we will perform a series of injections into the treatment area(s). The treatment is quick, usually only taking about 15-30 minutes to complete, depending on the number of treatment areas.

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Charlotte Mack, DNP, APRN

Jennifer J. Janiga Image

Jennifer J. Janiga, MD, FAAD

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After Your Restylane Defyne Procedure

There is minimal downtime and recovery after Restylane injections. Patients may experience mild swelling and bruising following treatment, which will resolve with time. It is recommended that patients avoid strenuous exercise and excess sun exposure for 24 hours following treatment to reduce swelling and maintain results. Patients can immediately return to work and other daily activities.

What to Expect After Your Restylane Defyne Procedure

Restylane Defyne immediately adds volume, but the best results will be seen after two weeks, once the filler has settled. The appearance of your skin will remain youthful for up to 12 months, and injections can be scheduled annually for regular maintenance. Patients can expect natural-looking results customized to their unique facial structure and features.

Why Choose JanigaMDs for Your Restylane Injections?

Choosing JanigaMDs for your injectable procedure with Restylane means working with a practice that combines medical expertise with an artistic approach to aesthetics. JanigaMDs is uniquely positioned as the only practice in Northern Nevada to host both a board-certified plastic surgeon and a board-certified dermatologist, giving patients access to a full spectrum of cosmetic expertise, from injectables to advanced surgical options, under one roof. This collaborative environment ensures that your Restylane injections are part of a comprehensive plan designed to deliver safe, effective, and natural-looking results that support long-term confidence.

Non-surgical medspa treatments are led by Dr. Jennifer Janiga, a board-certified dermatologist whose training and years of experience ensure that each treatment is tailored to your unique facial concerns and desired result. She received her medical degree at the University of Nevada, Reno School of Medicine, before completing a residency in Dermatology at the Henry Ford Health System Department of Dermatology. Dr. Janiga continues to stay knowledgeable about the latest advancements in cosmetic care as a Fellow of the American Academy of Dermatology and a member of prestigious organizations like the American Society of Dermatologic Surgery and Alpha Omega Alpha Medical Honor Society.

Dr. Janiga’s commitment to excellence and individualized, compassionate care has been recognized through numerous distinctions and awards. This includes repeated awards for Castle Connolly Top Doctor — Dermatologist, Best of Reno Dermatologist, Top Dermatologist, Exceptional Women in Medicine, and a listing on the American Registry of America’s Most Honored Professionals — Top 5%.

Under Dr. Janiga’s guidance, Restylane dermal fillers are expertly placed to help smooth lines, correct volume loss, and create a more balanced contour that enhances your natural features. Whether addressing nasolabial folds, cheek volume, or subtle facial hollows, Dr. Janiga focuses on achieving a refreshed appearance while maintaining authenticity. The goal of treatment is thoughtful correction that complements your facial anatomy and helps you look like a refreshed, more youthful version of yourself.

Learn More About Restylane Defyne at JanigaMDs

If you are interested in learning more about Restylane Defyne for a younger-looking you, contact our office today at 775-364-0224 to schedule your initial consultation. Our office is conveniently located in Reno, NV, and is easily accessible to patients across Nevada.

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"Excited to keep seeing her!"

Highly recommend the nurse practitioner Charlotte for all your skin care needs! I had never had Botox before so I was a little nervous about it. She made me feel comfortable and did an excellent job! I went back for a touch up after the first time I got it and she was able to fix exactly what was bothering me! Excited to keep seeing her 🙂

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"Cannot say enough"

I have been seeing Dr. Jennifer for quite a few years now for everything from suspicious moles to acne to now the fun, confidence boosting, not look my age stuff. I cannot say enough about the professionalism and efficiency of the staff, the cleanliness of the facility, Dr. Jen’s knowledge and skill and my results!

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"Highly, highly recommend!"

I absolutely love Dr. Jennifer Janiga. She’s always so kind, caring, helpful, thorough and knowledgeable. I feel like there just aren’t enough words to describe what a wonderful doctor she is! I’ve been seeing her for almost 5 years now and have never once felt awkward with her or like there are any questions not worth asking or worth her time to answer. We highly, highly recommend her to everyone who’s looking for a dermatologist!

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"Very Happy with My Results"

I’ve had microneedling, fillers, and Botox with Charlotte and I am very happy with the results. Charlotte is always so informative and answers all of my questions. I really like her conservative approach and recommendations. She is friendly and we always have great conversation!

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by Dr. Jennifer J. Janiga

Clearing Up Skin Care

Discover Clearing Up Skin Care by Dr. Jennifer Janiga—a no-nonsense guide to understanding your skin, choosing the right products and treatments, and building a routine that truly works for you. Pick up a copy in our office or purchase online to start building a routine that works.

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Beauty Fusion Consultation

JanigaMDs is the only practice in Reno where patients can consult with both a board-certified dermatologist and a board-certified plastic surgeon in one visit.

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Experience the best of both worlds

Founded in 2010, the team at JanigaMDs has been proven to provide the utmost care for all patients. With a 4.7 rating over almost 700 reviews, JanigaMDs is the premier aesthetic practice in Northern Nevada.

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